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The central theme of our research is functional surfaces and interfaces. It lies at the interface of organic chemistry, materials chemistry, and nanotechnology. We develop new methods for the immobilization of synthetic polymers, small molecules, and biomolecules, and conduct fundamental studies to better understand the surface chemistry that governs the immobilization processes. We are also developing methodologies to create surfaces that can provide functions such as biocompatibility and molecular recognition for biomaterial and biomedical applications.
Surface chemistry is inherently multidisciplinary, therefore, our research involves a variety of activities including organic/polymer synthesis, materials characterization, microlithography, and surface analysis. We collaborate with colleagues in biology, physics, and engineering applying our surface techniques in a wide range of bioanalytical and nanomaterial applications.
For detailed and updated information of research activities in our laboratory, visit
http://www.chem.pdx.edu/~yanm/Research.html
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Yan, M. "Photochemically Initiated Single Polymer Immobilization," Chem. Eur. J., 2007, 13, 4138-4144.
Pei, Z.; Yu, H.; Theurer, M.; Walden, A.; Nilsson, P.; Yan, M.; Ramström, O. "Photogenerated Carbohydrate Microarrays", ChemBioChem 2007, 8, 166-168.
Liu, L.; Engelhard, M. H.; Yan, M. "Surface and Interface Control on Photochemically Initiated Immobilization", J. Am. Chem. Soc. 2006, 128, 14067-14072.
Liu, L.; Yan, M. "A General Method for the Covalent Immobilization of Single Polymers," Angew. Chem. Int. Ed. 2006, 45, 6207-6210.
Molecularly Imprinted Materials-Science and Technology, Eds. Yan, M.; Ramström, O. Marcer Dekker Inc.: New York, 2005.
Chen, Y-C; Wang, Z.; Yan, M.; Prahl, S. "Fluorescence Anisotropy Studies of Molecularly Imprinted Polymers," Luminescence 2006, 21, 7-14.
Harnish, B.; Robinson, J.; Pei, Z.; Ramström, O.; Yan, M. "UV-Cross-Linked Poly(4-vinylpyridine) Thin Films as Reversibly Responsive Surfaces," Chem. Mater. 2005, 17, 4092-4096.
Graupner, R.; Yan, M. "A Theoretical Model for Photochemically Immobilized Macromolecular Layers on Solid Surfaces," Langmuir, 2004, 20, 8675-8680.
Chen, Y.-C. Brazier, J. J.; Yan, M.; Bargo, P. R.; Prahl, S. A. "Sensor Design of Optical Molecularly Imprinted Polymers," Sens. Actuators, B, 2004, 102, 107-116.
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